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Idiopathic male infertility is strongly associated with aberrant methylation of MEST and IGF2/H19 ICR1
International Journal of Andrology, 11/03/09
Poplinski A et al. – Idiopathic male infertility is strongly associated with imprinting defects at IGF2/H19 ICR1 and MEST, with aberrant MEST methylation being a strong indicator for sperm quality. The male germ cell thus represents a potential source for aberrant epigenetic features in children conceived via ART.
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