PA Medical News about Fatty Liver

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Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: Results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial
Hepatology, 11/02/09

Ratziu V et al. – Rosiglitazone has a substantial antisteatogenic effect in the first year of treatment without additional benefit with longer therapy despite a maintained effect on insulin sensitivity and transaminase levels. This suggests that improving insulin sensitivity might not be sufficient in NASH and that additional targets of therapy for liver injury should be explored.

Nonalcoholic fatty liver disease: Quantitative assessment of liver fat content by computed tomography, magnetic resonance imaging and proton magnetic resonance spectroscopy
Journal of Digestive Diseases, 10/29/09 Relevance Score: 69%

Synergistic effect of fatty liver and smoking on metabolic syndrome
World Journal of Gastroenterology, 11/17/09 Relevance Score: 68%

Serum proteomics and biomarker discovery across the spectrum of nonalcoholic fatty liver disease
Hepatology, 11/04/09 Relevance Score: 68%

Decreased Liver Fatty Acid delta-6 and delta-5 Desaturase Activity in Obese Patients
Obesity, 11/03/09 Relevance Score: 67%

Prevention of I/R injury in fatty livers by ischemic preconditioning is associated with increased mitochondrial tolerance: the key role of ATPsynthase and mitochondrial permeability transition
Transplant International, 10/22/09 Relevance Score: 67%