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See Latest ArticlesLong-term outcomes of positive fluorescence in situ hybridization tests in primary sclerosing cholangitis
Hepatology, 11/02/09
Lindor KD et al. – In PSC patients, the presence of a dominant stricture plus FISH polysomy has a specificity of 88% for CCA. Patients with FISH showing trisomy or tetrasomy have a similar outcome to patients with negative FISH. FISH testing should be used selectively in patients with other signs indicating CCA and not as a screening tool in all PSC patients undergoing endoscopic retrograde cholangiopancreatography (ERCP).
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