PA Medical News about HIV Bone Density

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Bone health in HIV infection
British Medical Bulletin, 10/30/09

Pollock E et al. – The prevalence of low bone mineral density (BMD) and fracture is increased in the HIV–positive population. The pathogenesis is multifactorial; there is some evidence that HIV infection is an independent risk factor and that highly active antiretroviral therapy has adverse skeletal effects. Physicians should routinely review the bone health of all HIV patients. More studies of the mechanisms of bone loss, the skeletal effects of antiretroviral therapy and the therapeutic outcome of bone–protective therapy in HIV–positive individuals are needed.

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