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See Latest ArticlesBoth nongenomic and genomic effects are involved in estradiols enhancing the phenotype of smooth muscle cells in cultured prostate stromal cells
The Prostate, 10/29/09
Zhang Z et al. – Estrogen could promote the expression of TGF–1 in PRSCs through nongenomic activation of MAPK pathway, and in turn enhance the SMC phenotype. Besides for this nongenomic effect, estrogen can also enhance the SMC phenotype through classical genomic action.
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