PA Medical News about Acne Vulgaris

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Management of acne vulgaris: an evidence-based update
Clinical and Experimental Dermatology, 11/02/09

Ingram J et al. – Photodynamic therapy, phototherapy and laser therapy cannot be recommended universally for acne until minimal postinflammatory pigmentation and longer–term benefit can be shown, especially with current high costs. Development of non–antibiotic therapies is preferable to minimize the risk of community antibiotic resistance. Future trials should use active comparators at optimum doses and avoid noninferiority comparisons unless appropriately powered. Trials need to shift from using multiple, unvalidated outcome measures to including patient–reported and quality–of–life outcomes, and all trials should be registered on a public clinical–trials database.