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Claassen J – Refractory status epilepticus (RSE) is associated with a high risk of poor outcome and treated by most neurointensivists with continuous intravenous antiepileptic medications. Continuous EEG monitoring has allowed us to unveil a number of epileptiform patterns of less certain significance. These have been labeled ictal to interictal continuum, many of which are associated with poor outcome. It is unclear to which extent individual patterns are epiphenomena or lead to additional brain injury.

   

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