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Epithelial differentiation of adipose-derived stem cells for laryngeal tissue engineering
The Laryngoscope, 10/27/09
Long JL et al. – A three–dimensional structure of fibrin and adipose–derived stem cells was created as a prototype vocal fold replacement. Two segregated cell phenotypes occurred, producing a bilayered structure resembling epithelium over lamina propria. This preliminary work demonstrates the feasibility of tissue engineering to produce structures for vocal fold replacement.
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