PA Medical News about Brain Hemorrhage, Traumatic Pediatrics

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Treatment of traumatic brain injury in pediatrics
Current Treatment Options in Neurology, 10/29/09

Madikians A et al. – The primary goal in treating any pediatric patient with severe traumatic brain injury (TBI) is the prevention of secondary insults such as hypotension, hypoxia, and cerebral edema. Despite the publication of guidelines, significant variations in the treatment of severe TBI continue to exist, especially in regards to intracranial pressure (ICP)–guided therapy. This variability in treatment results mainly from a paucity of data from which to create standards and from the heterogeneity inherent in pediatric TBI. The approach to management of severe TBI based on the published guidelines should be focused on ICP control, which should ultimately improve cerebral perfusion pressure. After identifying and surgically evacuating expanding hematomas, the first–tier treatment approach requires placing an ICP monitor.

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Clinical management and functional neuromonitoring in traumatic brain injury in children
Current Opinion in Pediatrics, 10/23/09 Relevance Score: 82%

Pressure autoregulation, intracranial pressure, and brain tissue oxygenation in children with severe traumatic brain injury
Journal of Neurosurgery: Pediatrics, 11/09/09 Relevance Score: 80%

Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study
The Lancet, 10/05/09 Relevance Score: 80%

Elevation of Matrix Metalloproteinases 3 and 9 in Cerebrospinal Fluid and Blood in Patients With Severe Traumatic Brain Injury
Neurosurgery, 10/02/09 Relevance Score: 80%

Diagnostic value of S100B and neuron-specific enolase in mild pediatric traumatic brain injury
Journal of Neurosurgery: Pediatrics, 10/06/09 Relevance Score: 79%