PA Medical News about macular degeneration

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Autocrine Vascular Endothelial Growth Factor Enhances Survival of Retinal Pigment Epithelium Cells under Oxidative Stress via the VEGF R-2/PI3K/Akt
Investigative Ophthalmology and Visual Science, 11/05/09

Byeon SH et al. – Autocrine VEGF–A enhanced RPE cell survival under oxidative stress; the autocrine VEGF–A/VEGF R2/PI3K/Akt pathway is involved. Neutralization of VEGF–A signaling, as in age–related macular degeneration eyes, may influence RPE cell survival.

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Mutation- and tissue-specific alterations of RPGR transcripts

Intravitreal bevacizumab for treatment-naive patients with subfoveal occult choroidal neovascularization secondary to age-related macular degeneration
Retina, 11/11/09 Relevance Score: 68%

Statin Use and the Incidence of Advanced Age-Related Macular Degeneration in the Complications of Age-Related Macular Degeneration Prevention Trial
Ophthalmology, 10/28/09 Relevance Score: 68%

siRNA therapeutics for age-related macular degeneration: promises and pitfalls
Expert Review of Ophthalmology, 10/22/09 Relevance Score: 68%

Bevacizumab vs Ranibizumab for Age-related Macular Degeneration: Early Results of a Prospective Double-Masked, Randomized Clinical Trial
American Journal of Ophthalmology, 10/07/09 Relevance Score: 67%

Efficacy of 12-month treatment of neovascular age-related macular degeneration with intravitreal bevacizumab based on individually determined injection strategies after three consecutive monthly injections
Acta Ophthalmologica, 11/11/09 Relevance Score: 66%