PA Medical News about Arteriovenous Malformations Lung Diseases

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Endovascular embolization with a vascular plug corrects a PAVM
JAAPA, 10/26/09

Hu S et al. – A pulmonary arteriovenous malformation (PAVM) is a rare, congenital vascular malformation. Historically, treatment is embolization with coils or a detachable balloon to prevent the risk of serious complications, such as cerebral embolism/infarct, brain abscess, paradoxical emboli, and high–output right–heart failure. In this patient case, lifestylelimiting symptoms, including dyspnea on exertion and epistaxis, were successfully treated with transcatheter embolization of a large PAVM using a recently developed device called a vascular plug...The vascular plug appears to be an effective tool for embolotherapy of simple PAVMs, particularly in cases with a single large feeding and draining vessel. These patients are at an increased risk of inadvertent embolization when coils or detachable occlusion balloons are used. Long–term results are not yet available; however, our patient will be closely followed with serial CT by the pulmonology service for any indications of recanalization of the PAVM. Screening was recommended for her family members.

A case of horseshoe lung and complex congenital heart disease in a term newborn
Pediatric Radiology, 10/01/09 Relevance Score: 79%

Dabigatran, a direct thrombin inhibitor, demonstrates antifibrotic effects on lung fibroblasts
Arthritis & Rheumatism, 11/11/09 Relevance Score: 69%

An intrathoracic arteriovenous malformation discovered as an extremely uncommon reason of neonatal congestive cardiac failure
Cardiology in the Young, 10/23/09 Relevance Score: 69%

Notch-1 signalling is activated in brain arteriovenous malformations in humans
Brain, 10/23/09 Relevance Score: 69%

The putative role of the venous system in the genesis of vascular malformations
Neurosurgical Focus, 11/10/09 Relevance Score: 68%