PA Medical News about prostate cancer

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Enzyme inhibitor effective against refractory prostate cancer
Urology Times, 11/03/09

Kuznar W – Previous clinical trials have shown that specific inhibition of CYP17 is safe and has antitumor activity in up to 70% of castrate patients with advanced prostate cancer who were resistant to endocrine therapies. The phase II study reported here included 47 patients in whom androgen deprivation therapy had failed. All had had prior docetaxel (Taxotere) chemotherapy. They received abiraterone acetate orally, 1,000mg/day in 28–day cycles. Stable doses of glucocorticoids were allowed.

Risk of dying from prostate cancer in men randomized to screening
Cancer, 10/13/09 Relevance Score: 72%

Validation in a Multiple Urology Practice Cohort of the Prostate Cancer Prevention Trial Calculator for Predicting Prostate Cancer Detection
The Journal of Urology, 11/13/09 Relevance Score: 71%

A prospective study of lifetime physical activity and prostate cancer incidence and mortality
British Journal of Cancer, 11/02/09 Relevance Score: 71%

Association of 17 prostate cancer susceptibility loci with prostate cancer risk in Chinese men
The Prostate, 11/02/09 Relevance Score: 71%

Prostate specific antigen for early detection of prostate cancer: longitudinal study
British Medical Journal, 10/08/09 Relevance Score: 71%