Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Recommendations on the use of 18F-FDG PET in oncology 3. Use of Antiemetic Agents in Acute Gastroenteritis 4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 5. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease
Your Article Summary
See Latest ArticlesOnce-daily initiation with biphasic insulin aspart 30 versus insulin glargine in patients with type 2 diabetes inadequately controlled with oral drugs: an open-label, multinational RCT
Current Medical Research and Opinion, 10/22/09
Strojek K et al. – With respect to HbA1c, BIAsp 30 fulfilled the statistical criteria for non–inferiority and superiority to insulin glargine and, according to pre–defined criteria, the improvements in HbA1c are considered clinically equivalent. Subjects had an increased risk of minor nocturnal hypoglycemia with BIAsp 30. There were no differences in treatment satisfaction between the two groups.
Krzysztof Strojek, 10/22/09
| Hypoglycemic treatment of type 2 diabetic patients must be focused on normalization of blood glucose without adverse effects. The study showed that initiation of insulin should be individualized. Both algorithms brought the similar treatment satisfaction while BIAsp30 was associated with better glycemic control. On the other hand in the group of patients with higher risk of hypoglycemia, especially nocturnal, insulin initiation with glargine should be considered as alternative option. |
Related Articles
Rationale, Design, and Baseline Data of the Insulin Glargine (Lantus) Versus Insulin Detemir (Levemir) Treat-To-Target (L2T3) Study: A Multinational, Randomized Noninferiority Trial of Basal Insulin Initiation in Type 2 Diabetes
Diabetes Technology & Therapeutics, 11/17/09
Relevance Score: 94%
Effect of the urotensin-II receptor antagonist palosuran on secretion of and sensitivity to insulin in patients with Type 2 diabetes mellitus
British Journal of Clinical Pharmacology, 10/22/09
Relevance Score: 94%
Cigarette smoking is an independent risk factor for type 2 diabetes: a four-year community-based prospective study
Clinical Endocrinology, 10/16/09
Relevance Score: 94%
Postprandial Vascular Effects of Viaject compared with Insulin Lispro and Regular Human Insulin in Patients with Type 2 Diabetes Mellitus
Diabetes Care, 10/14/09
Relevance Score: 94%
Comparison of Incidence of Acute Myocardial Infarction in Patients With Type 2 Diabetes Mellitus Following Initiation of Neutral Protamine Hagedorn Insulin Versus Insulin Glargine
The American Journal of Cardiology, 10/01/09
Relevance Score: 94%
Today in Clinical Pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
Sertraline treatment is associated with an improvement in depression and health-related quality of life in chronic peritoneal dialysis patients
International Urology and Nephrology, 12/10/09
Opioids for the Management of Severe Chronic Nonmalignant Pain in Children: A Retrospective 1 Year Practice Survey in a Childrens Hospital
Pain Medicine, 12/10/09
Non-fatal overdose of duloxetine in combination with other antidepressants and benzodiazepines
World Journal of Biological Psychiatry, 12/10/09
Today in Endocrinology...keeping you current
Receive free subspecialty "5-minute updates" via email
The ENPP1 K121Q polymorphism determines individual susceptibility to the insulin-sensitising effect of lifestyle intervention
Diabetologia - Clinical and Experimental Diabetes and Metabolism, 12/10/09
False Positive test Results for Pheochromocytoma from 2000 to 2008
Experimental and Clinical Endocrinology & Diabetes, 12/10/09
Does Normal Thyroid Gland by Ultrasonography match with Normal Serum Thyroid Hormones and Negative Thyroid Antibodies
Experimental and Clinical Endocrinology & Diabetes, 12/10/09
Sponsor
Article Search
Sponsor
Sponsor