PA Medical News about Lichen Planus, Oral

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Update on oral lichen planus
Expert Review of Dermatology, 10/14/09

Carrozzo M et al. – Oral lichen planus (OLP) is a relatively common chronic inflammatory disorder with a low risk of associated malignancy. A genetic predisposition linked to Th1 cytokine polymorphisms may predispose to the T–cell–mediated immunological response to an induced antigenic change that is supposed to cause OLP lesions. Amalgam restorations, hepatitis C virus and systemic medications may be etiologic factors.