PA Medical News about rheumatoid arthritis

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Radiologic observation: repair of focal bone erosions after humanized antitumor necrosis factor antibody adalimumab therapy in a patient with rheumatoid arthritis
Clinical Rheumatology, 10/22/09

Ahn IE et al. – Erosions of the bone and cartilage are considered as a cardinal feature of rheumatoid arthritis (RA) leading to joint destruction and functional limitations. This report is a radiologic observation of distinguishable bone erosion repair with concomitant increase of radio–opacity of trabecular bones. The patient's dramatic structural retrieval is a discrepant, yet notable case pivoting the previous belief on the skeletal restoration capacity of anti–TNF antibody into a circulating cytokine–dependent manner.

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