PA Medical News about Pain, Postoperative Adult Tonsillectomy Lornoxicam Tramadol

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Effects of preoperative lornoxicam versus tramadol on postoperative pain and adverse effects in adult tonsillectomy patients
Agri, 10/01/09

Arslan M et al. – Preoperative 8 mg lornoxicam was more effective than 50 mg tramadol with respect to early postoperative tonsillectomy pain in adult patients, and side effects were similar.

Methods

Prospective, double blind, randomized, clinical research.
40 American Society of Anesthesiologists (ASA) status I–II patients of both gender, aged 18–55 years, were included.
Tonsillectomy patients were divided into two groups: Those in Group L received 8 mg lornoxicam and in Group T received 50 mg tramadol intravenously just before induction of general anesthesia.
Postoperative pain on swallowing was scored by a blinded anesthesiologist using Verbal Rating Scale (VRS) on arrival in the Post Anesthesia Care Unit (T0), at 30 min (T1), 1h (T2), 2h (T3), 3h (T4), 4h (T5), 5h (T6), and 6h (T7) thereafter.
During the first postoperative 6 hours, when VRS >=2, 1mg.kg–1 im meperidine was used as a rescue analgesic.

Results

T1 and T2 pain scores in Group T were higher than in Group L (p=0.049, p=0.007, respectively).
The number of patients requiring rescue analgesics during the first 6 hours in Group L was lower than in Group T.
Nausea–vomiting, bleeding and postoperative hemorrhage values were similar between Group L and Group T.