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Quality of life and depression among metastatic breast cancer patients
Medical Oncology, 10/05/09
Slovacek L et al. – The pilot study evaluated the level of the global quality of life (QoL) and the incidence and the relevance of the depression among metastatic breast cancer patients in a programme of palliative cancer care. The results showed that subsist association between metastatic breast cancer, depression, and the low level of the global QoL.
Methods- Study is prospective and cross-sectional
- Dates obtained during year 2008 among 41 patients
- mean age of all 41 subjects was 58 years old (aged 41–80 years old)
- The Czech version of Zung self-rating depression scale performed for evaluation of depression
- Czech version of generic European Quality of Life Questionnaire EQ-5D performed for evaluation of level of global QoL
- Statistical evaluation presents that mean ZSDS (Zung self-rating depression score) certifies presence of signs of moderate depression among metastatic breast cancer patients (ZSDS range was 60–69)
- Incidence of depression was 61% (25 of all 41 subjects)
- Relevance of depression is characterized: the severe depression was proved in 5 of all 25 subjects, the moderate depression in 10 of all 25 subjects, and the mild depression in 10 of all 25 subjects
- Global QoL among metastatic breast cancer patients is very low level
- Mean EQ-5D score (dimension of QoL) was 55%
- Mean EQ-5D VAS (subjective health status) was 59.2%
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