PA Medical News about Andrographolide

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Andrographolide: A New Plant-Derived Antineoplastic Entity on Horizon
Evidence-based Complementary and Alternative Medicine , 09/23/09

Varma A et al. – In vitro studies demonstrate the capability of the compound of inducing cell–cycle arrest and apoptosis in a variety of cancer cells at different concentrations. Andrographolide also shows potent immunomodulatory and anti–angiogenic activities in tumorous tissues. Synthetic analogues of the compound have also been created and analyzed, which have also shown similar activities. Although it is too early to predict its future in cancer chemotherapy, the prologue strongly recommends further research on this molecule to assess its potential as a prospective anticancer agent.