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Relation between fractures and mortality: results from the Canadian Multicentre Osteoporosis Study
Canadian Medical Association Journal, 09/01/09

Ioannidis G et al. – Vertebral and hip fractures are associated with an increased risk of death. Interventions that reduce the incidence of these fractures need to be implemented to improve survival.

• A 5–year observational cohort study.
• 7753 randomly selected people (2187 men and 5566 women) aged 50 years and older.
• Incident fractures were identified on the basis of validated self–report and were classified by type (vertebral, pelvic, forearm or wrist, rib, hip and "other").
• The authors subdivided fracture groups by the year in which the fracture occurred during follow–up; those occurring in the fourth and fifth years were grouped together.
• The authors examined the relation between the time of the incident fracture and death.
• fourth bullet
• first bullet

• Compared with participants who had no fracture during follow–up, those who had a vertebral fracture in the second year were at increased risk of death.
• At risk were those who had a hip fracture during the first year.
• Among women, the risk of death was increased for those with a vertebral fracture during the first year or the second year of follow–up.
• The risk of death was also increased among women with hip fracture during the first year of follow–up.

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