PA Medical News about COPD; theophylline; mortality

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Mortality Risk in Patients Receiving Drug Regimens with Theophylline for Chronic Obstructive Pulmonary Disease
Pharmacotherapy, 08/26/09

Lee TA et al. – Patients receiving regimens that included theophylline had slightly increased risks of mortality, COPD exacerbations, and COPD hospitalizations compared with patients receiving the same regimens without theophylline. However, the benefits of theophylline on other factors, including symptoms, quality of life, and activities of daily living, were not measured. Clinicians should consider all of the potential benefits and harms associated with theophylline when making treatment recommendations.

Bone mineral density and fractures in older men with chronic obstructive pulmonary disease or asthma
Osteoporosis International, 10/13/09 Relevance Score: 92%

Interaction in COPD experiment (ICE): A hazardous combination of cigarette smoking and bronchodilation in chronic obstructive pulmonary disease
Medical Hypotheses, 10/08/09 Relevance Score: 91%

Molecular Characterization of Chronic Obstructive Pulmonary Disease-Related Non-Small Cell Lung Cancer Through Aberrant Methylation and Alterations of EGFR Signaling
Annals of Surgical Oncology, 10/23/09 Relevance Score: 90%

Tiotropium HandiHaler in the treatment of COPD: A safety review
International Journal of COPD, 10/29/09 Relevance Score: 89%

Living with advanced chronic obstructive pulmonary disease: patients concerns regarding death and dying
Palliative Medicine, 10/16/09 Relevance Score: 89%