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Cancer incidence and exposure to 4,4'-methylene-bis-ortho-chloroaniline (MbOCA)
Occupational Medicine, 08/31/09
Dost A et al. – The findings for bladder cancer should be treated with caution as they relate to a relatively early period of follow–up and are based on very small numbers.
Methods- A cohort of 308 male production workers from seven factories have been enumerated.
- All employees had a minimum of 12 months employment and were first employed at one of the participating factories in the period 1973–2000.
- Mortality and cancer incidence data for the period 1979–2007 were compared with expected values based on national rates.
- Mortality from all cancers combined was below the expected value.
- There was a single death from bladder cancer.
- The incidence of all cancers combined was also below expectation.
- Site–specific incidence was unexceptional except there was a non–significant excess of bladder cancer based on two cases.
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