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See Latest ArticlesClinical Implications of Microsatellite Instability and MLH1 Gene Inactivation in Sporadic Insulinomas
Journal of Clinical Endocrinology and Metabolism, 07/02/09
Chen YJ et al. - High frequency of MSI occurred in sporadic insulinomas. The silencing of MLH1 gene may partially contribute to the MSI-H in the tumors. Assessing MSI-H and expressions of MLH1 could be used to distinguish benign and malignant insulinomas and to predict the outcome of patients.
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