Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Recommendations on the use of 18F-FDG PET in oncology 3. Use of Antiemetic Agents in Acute Gastroenteritis 4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 5. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease
Your Article Summary
See Latest ArticlesNovel treatment strategies for malignant gliomas using neural stem cells
Neurotherapeutics, 07/01/09
Oh MC et al. - In a review of novel treatment strategies for malignant gliomas using neural stem cells (NSCs), it was concluded that these studies and others on the basic biology of both brain tumor stem cells (BTSCs) and NSCs will be crucial to expanding treatment strategies for malignant gliomas.
Methods- Identification and characterization of endogenous NSCs, especially those in the adult human brain, have inspired new ideas for selectively targeting and destroying malignant gliomas.
- Gliomas consist of a heterogeneous population of cells, and some of these cells have characteristics of cancer stem cells.
- These BTSCs share certain characteristics with normal NSCs.
- It is still unclear whether malignant gliomas in human pts originate from these aberrant BTSCs.
- Cellular and molecular similarities between BTSCs and normal NSCs suggest a common research landscape underlying both normal and cancer stem cell biology, wherein findings of 1 field are relevant to the other.
- The natural tropism of NSCs to gliomas has generated the idea that modified NSCs can deliver modified genes to selectively destroy malignant brain tumor cells, and even BTSCs, while leaving healthy surrounding neurons intact.
Today in Hematology/Oncology...keeping you current
Receive free subspecialty "5-minute updates" via email
Risk of dying from prostate cancer in men randomized to screening
Cancer, 10/13/09
Local excision alone without irradiation for ductal carcinoma in situ of the breast: A trial of the Eastern Cooperative Oncology Group
Journal of Clinical Oncology, 10/19/09
Nonsteroidal anti-inflammatory drugs
Cancer, 10/16/09
Today in Neurology...keeping you current
Receive free subspecialty "5-minute updates" via email
Antithrombotic medication for stroke prevention
Expert Review of Cardiovascular Therapy , 10/20/09
Escitalopram and Venlafaxine for the Prophylaxis of Migraine Headache Without Mood Disorders
Clinical Neuropharmacology, 10/02/09
Nortriptyline and gabapentin, alone and in combination for neuropathic pain: a double-blind, randomised controlled crossover trial
The Lancet, 10/13/09
Sponsor
Article Search
Sponsor
Sponsor