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Guideline supports long-term use of medication to lower prostate cancer risk
JAMA, 05/08/09
Mitka M - In a guideline on long-term use of medication to lower prostate cancer (PCa) risk, it was announced that the new guideline calls for physicians who screen asymptomatic men for PCa to advise them about a multiyear regimen of medication that may reduce their risk of developing the disease.
Methods- The guideline, issued February 24 by an expert panel jointly convened by the American Society of Clinical Oncology (ASCO) and the American Urological Association (AUA), focuses on men with a prostate-specific antigen (PSA) level of ≤3.0 ng/mL who are regularly screened with a PSA test or who are considering receiving an annual PSA test.
- This guideline calls for physicians who screen asymptomatic men for PCa to advise them about a multiyear regimen of medication that may reduce their risk of developing the disease.
- The guideline states that current evidence suggests the medication offers no benefit in reducing PCa mortality or overall mortality.
- Nor does it dismiss the possibility that the drug might actually increase the risk of getting a higher-grade, and more deadly, form of this cancer.
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