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Sweet Syndrome as a Manifestation of Azathioprine Hypersensitivity
Mayo Clinic Proceedings, 09/05/08
Rokea A et al. - The authors describe 3 patients, 2 with inflammatory bowel disease and 1 with myasthenia gravis, who developed febrile pustulosis consistent with Sweet syndrome 1 to 2 weeks after treatment with azathioprine. Antibiotic therapy failed in all patients, but Sweet syndrome resolved with drug withdrawal and prednisone therapy. Because azathioprine is widely used, clinicians should be aware of this adverse reaction.
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