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Optimizing selective cerebral perfusion: Deleterious effects of high perfusion pressures
The Journal of Thoracic and Cardiovascular Surgery, 04/15/08
Halstead JC et al. - Selective cerebral perfusion at 50 mm Hg provides neuroprotection superior to that at higher pressures. The increased cerebral blood flow with higher-pressure selective cerebral perfusion is associated with cerebral injury, reflected by high post–cardiopulmonary bypass cerebral oxygen metabolism and poorer neurobehavioral recovery.
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