The Glass Half Empty or Half Full—How Effective Are Long-Term Intrathecal Opioids in Post-herpetic Neuralgia Zacest A et al. - While a complex therapy, long-term use of intrathecal opioids is well tolerated, doses are titratable, administration is safe, and may help relieve severe short- and long-term neuropathic pain in selected PHN patients. Whether the addition of newer investigational intrathecal agents could improve these results is yet to be determined. [more...]