Screening for Hepatitis B Virus Infection in Pregnancy: U.S. Preventive Services Task Force Reaffirmation Recommendation Statement
Reaffirmation of the 2004 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for hepatitis B virus hepatitis B virus infection in pregnancy. The USPSTF performed a brief literature update, including a search for new and substantial evidence on the benefits and harms of screening pregnant women for hepatitis B virus infection. The USPSTF recommends screening for hepatitis B virus (HBV) infection in pregnant women at their first prenatal visit. (This is a grade A recommendation.)
Screening Tests: Serologic identification of hepatitis B surface antigen (HBsAg). Reported sensitivity and specificity are greater than 98%.
Timing of Screening:- Order HBsAg testing at the first prenatal visit.
- Rescreen women with unknown HBsAg status or new or continuing risk factors at admission to hospital, birth center, or other delivery setting.
Interventions: - Administer hepatitis B vaccine and hepatitis B immune globulin to HBV-exposed infants within 12 hours of birth.
- Refer women who test positive for counseling and medical management.
- Counseling should include information about how to prevent transmission to sexual partners and household contacts.
- Reassure patients that breastfeeding is safe for infants who receive appropriate prophylaxis.
Implementation: Establish systems for timely transfer of maternal HBsAg test results to the labor and delivery and newborn medical records. [more...]
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