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Preliminary Observations of a Novel Topical Oil with Analgesic Properties for Treatment of Acute and Chronic Pain Syndromes
Pain Practice, 03/04/2010
Exclusive author commentary
Review Article
Pergolizzi JV et al. – Essential oxygen oil (OxyRub from CreoMed Inc., Naples, FL, U.S.A.) is a novel topical analgesic currently commercially available in Europe and now available in the U.S.A. It represents an important alternative to other treatments (nonsteroidal anti–inflammatory drugs, acetaminophen, menthol, camphor) for managing mild to moderate acute and chronic pain. Several clinical trials of this oil will be reviewed...Based on studies completed, essential oxygen oil has shown itself to be safe, has demonstrated positive analgesic effects for the treatment of acute and chronic pain, and has improved oxygen content in the skin as well as other dermatological parameters.
Joseph Pergolizzi, MD (03/10/2010) comments:
Essential oxygen oil has been clinically proven safe and effective with a novel mechanism of action based on increasing oxygen to the microcirculatory system. As such, this oil represents an alternative to other topical analgesics, whose safety and effectiveness results have been mixed. Although “novel” to the U.S. market, essential oxygen oil has been available over-the-counter in Europe for over a decade. Essential oxygen oil may represent an important alternative in over-the-counter pain relief products. Certainly its introduction to the U.S. market is timely in the wake of reports on potential dangers of such over-the-counter analgesics as NSAIDs and acetaminophen and with growing awareness of prescription pain killer abuse. Essential oxygen oil appears to be a promising “import” to our analgesic armamentarium.
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