The development of a survey to measure completeness of response to migraine therapy

Headache: The Journal of Head and Face Pain, 05/02/2012

The completeness of response survey (CORS) is capable of demonstrating advantages of more comprehensive migraine therapies over traditional therapies, which are primarily focused on the resolution of headache pain, by addressing the frequency and speed with which the most common migraine symptoms are resolved and patients' return to normal functioning. This research shows evidence for the value and utility for the CORS static and comparative items and components, and further evaluation is underway.

Methods

  • Data from an 8–site study comparing 147 patients' recent experiences with their current triptan therapy and 2 months of study treatment with a single–tablet formulation of sumatriptan/naproxen sodium were used to conduct a preliminary psychometric evaluation of the CORS.
  • The study included both modules of the CORS, the Headache Impact Test, the revised Patient Perception of Migraine Questionnaire, and a migraine diary.

Results

  • The CORS response categories in both the static and comparative modules demonstrated limited floor or ceiling effects and few missing values (<3%). X
  • Inter–item correlations, principal components analysis (component loading range: 0.62 to 0.95), and high estimates of internal consistency (alpha range: 0.88 to 0.94) for each composite score supported the structure and proposed scoring algorithm for the static module.
  • The pattern of correlations between the CORS static and comparative items and composites with the revised Patient Perception of Migraine Questionnaire items and subscales, as well as the relationships between responses to selected static CORS items and the migraine diary, supported the construct validity of the CORS.

Go to PubMed Go to Abstract Print Article Summary