1The effect of lower extremity nerve decompression on health-related quality of life and perception of pain in patients with painful diabetic polyneuropathy: a prospective randomized trialDiabetic Medicine  Clinical Article
2Effectiveness of dry needling on the lower trapezius in patients with mechanical neck pain: a randomized controlled trialArchives of Physical Medicine and Rehabilitation  Clinical Article
3A population-based, incidence cohort study of mid-back pain after traffic collisions: Factors associated with global recoveryEuropean Journal of Pain  Clinical Article
4Quantitative meta-analysis of grey matter anomalies in neuropathic painEuropean Journal of Pain  Clinical Article
5Genetics and the environment affect the relationship between depression and low back pain: A co-twin control study of Spanish twinsPain  Clinical Article
6Voluntary activation of trunk extensors appears normal in young adults who have recovered from low back painEuropean Journal of Pain  Clinical Article
7Effects of terbinafine and itraconazole on the pharmacokinetics of orally administered tramadolEuropean Journal of Clinical Pharmacology  Clinical Article
8Sickness absence due to back pain or depressive episode and the risk of all-cause and diagnosis-specific disability pension: A Swedish cohort study of 4,823,069 individualsEuropean Journal of Pain  Clinical Article
9Efficacy and cost-effectiveness: A study of different treatment approaches in a tertiary pain centreEuropean Journal of Pain  Clinical Article
10Migraine affects white-matter tract integrity: A diffusion-tensor imaging studyCephalalgia  Clinical Article

Show Me:

Tapentadol ER effective in alleviating pain of DN

As reported in Diabetes Care, tapentadol ER (100-250 mg bid) for 12 weeks resulted in increased pain relief in patients with moderate-to-severe diabetic neuropathy (n=166) compared to placebo.

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Clinical Pearls

Clinical Pearl from Smartest DocPatients with chronic non-specific low back pain exhibit divergent walking patterns.

Clinical Pearl from Smartest DocThe estimated prevalence of prescription opioid abuse among all US adults is 1.3%.

Clinical Pearl from Smartest DocFrovatriptan has a long elimination half-life of 26 hours.

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List