We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1How does pain lead to disability? A systematic review and meta-analysis of mediation studies in people with back and neck painPain, May 22, 2015  Clinical Article  Evidence Based Medicine  Review Article
2Opioid therapy in the treatment of chronic pain conditions in GermanyPain Physician, May 22, 2015  Full Text  Clinical Article
3Effect of strengthening versus balance-proprioceptive exercises on lower extremity function in patients with juvenile idiopathic arthritis: a randomized, single-blind clinical trialAmerican Journal of Physical Medicine & Rehabilitation, May 22, 2015  Clinical Article
4Do the gaps in the ligamentum flavum in the cervical spine translate into dural punctures? an analysis of 4,396 fluoroscopic interlaminar epidural injections Pain Physician, May 22, 2015  Full Text  Clinical Article
5A new transmucous-buccal formulation of acetaminophen for acute traumatic pain: A non-inferiority, randomized, double-blind, clinical trialPain Physician, May 22, 2015  Full Text  Clinical Article
6Self-reports of medication side effects and pain-related activity interference in patients with chronic pain: a longitudinal cohort studyPain, May 22, 2015  Clinical Article
7MicroRNA-873 inhibits morphine-induced macrophage apoptosis by elevating A20 expressionPain Medicine, May 22, 2015  Clinical Article
8Altered thermal grill response and paradoxical heat sensations after topical capsaicin applicationPain, May 22, 2015  Clinical Article
9Transplant-mediated enhancement of spinal cord GABAergic inhibition reverses paclitaxel-induced mechanical and heat hypersensitivityPain, May 22, 2015  Clinical Article
10Reversal of insular and microstructural nerve abnormalities following effective surgical treatment for trigeminal neuralgiaPain, May 22, 2015  Clinical Article

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Tapentadol ER effective in alleviating pain of DN

As reported in Diabetes Care, tapentadol ER (100-250 mg bid) for 12 weeks resulted in increased pain relief in patients with moderate-to-severe diabetic neuropathy (n=166) compared to placebo.

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Clinical Pearls

Clinical Pearl from Smartest DocIntradiscal biacuplasty uses cooled radiofrequency to ablate nociceptors in the posterior aspect of the intervertebral disc in discogenic back pain.

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