Ototoxicity in preterm infants: effects of genetics, aminoglycosides, and loud environmental noise
Journal of Perinatology, 08/10/2012
Zimmerman E et al. – This review provides a systematic analysis of the research in this area and elucidates the multifactorial mechanisms behind how mitochondrial DNA mutations, aminoglycosides and loud noise can potentiate ototoxicity in extremely preterm neonates. Recommended steps to minimize the risk of ototoxicity and improve clinical care for Neonatal Intensive Care Unit (NICU) infants are discussed.