Head and neck carcinoma in the United States
Cancer,

Ang KK et al. – Longitudinal Oncology Registry of Head and Neck Carcinoma (LORHAN) documented differences in patient characteristics and treatments between community and academic settings for a large series of patients in the United States.

Methods
  • Patients aged ≥18years were enrolled in the Longitudinal Oncology Registry of Head and Neck Carcinoma (LORHAN) after providing written informed consent if they had a confirmed diagnosis of new HNC and were scheduled to receive treatment other than surgery alone.

Results
  • Between 2005 and 2010, 100 centers enrolled 4243 patients, including 2612 patients (62%) from academic investigators and 1631 patients (38%) from community centers.
  • Initial treatments were radiation with concurrent chemotherapy (30%) or cetuximab (9%), adjuvant radiotherapy (21%), induction chemotherapy (16%), and other (24%).
  • Intensity modulated radiation therapy was the dominant radiation technique (84%).
  • Single-agent cisplatin was prescribed in nearly half of patients and more often in academic centers (53% vs 43% of patients; P<.0001).
  • Single-agent cetuximab was the next most common drug used (19%) and was prescribed more frequently in community settings (24% vs 17%; P=.0001).
  • The data rejected the 2 prospective hypotheses.

Please login or register to follow this author.
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

Your Unread Messages in Otolaryngology

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Otolaryngology Articles

1 Efficacy of honey in reduction of post tonsillectomy pain, randomized clinical trial International Journal of Pediatric Otorhinolaryngology , October 24, 2014    Clinical Article
Exclusive Author Commentary

2 Stroke after adenotonsillectomy in patients with undiagnosed moyamoya syndrome JAMA Otolaryngology—Head & Neck Surgery, October 9, 2014    Clinical Article

3 Standalone balloon dilation versus sinus surgery for chronic rhinosinusitis: A prospective, multicenter, randomized, controlled trial with 1-year follow-up The American Journal of Rhinology & Allergy, August 1, 2014    Clinical Article

4 Long-term follow up of sudden sensorineural hearing loss patients treated with intratympanic steroids: audiological and quality of life evaluation The Journal of Laryngology & Otology, September 9, 2014    Clinical Article

5 Long-term outcomes of endoscopic maxillary mega-antrostomy for refractory chronic maxillary sinusitis International Forum of Allergy & Rhinology, October 15, 2014    Clinical Article

6 Sinus culture poorly predicts resident microbiota International Forum of Allergy & Rhinology, October 14, 2014    Clinical Article

7 A randomized, controlled, blinded study of bioabsorbable steroid-eluting sinus implants for in-office treatment of recurrent sinonasal polyposis International Forum of Allergy & Rhinology, October 1, 2014    Clinical Article

8 Trends in orbital complications of pediatric rhinosinusitis in the United States JAMA Otolaryngology—Head & Neck Surgery, October 29, 2014    Clinical Article

9 The effect of radiofrequency turbinoplasty vs two other methods in the management of polypoid changes of the middle turbinate: A randomized trial International Forum of Allergy & Rhinology, September 4, 2014    Clinical Article

10 Effects of oral prednisolone on recovery after tonsillectomy The Laryngoscope, October 10, 2014    Clinical Article

11 Impact of functional endoscopic sinus surgery on the pulmonary function of patients with chronic rhinosinusitis: a prospective study Indian Journal of Otolaryngology and Head & Neck Surgery, October 20, 2014    Clinical Article

12 Complementary and alternative therapy (CAM) in the treatment of allergic rhinitis Current Allergy and Asthma Reports, October 3, 2014    Review Article

13 Indications for tonsillectomy: a 10 year retrospective review International Journal of Pediatric Otorhinolaryngology , October 21, 2014    Review Article

14 Current trends in perioperative antibiotic use: a survey of otolaryngologists Otolaryngology - Head and Neck Surgery, October 15, 2014    Clinical Article

15 Pharyngocutaneous fistula after total laryngectomy: A single-institution experience, 2001–2012 American Journal of Otolaryngology, September 26, 2014    Review Article

16 Economic evaluation of endoscopic sinus surgery versus continued medical therapy for refractory chronic rhinosinusitis The Laryngoscope, September 10, 2014    Clinical Article

17 Quality of life improvement from sinus surgery in chronic rhinosinusitis patients with asthma and nasal polyps International Forum of Allergy & Rhinology, October 2, 2014    Clinical Article

18 A double-blind randomised placebo-controlled trial of topical intranasal mometasone furoate nasal spray in children of adenoidal hypertrophy with otitis media with effusion American Journal of Otolaryngology, September 24, 2014    Clinical Article

19 Nasal steroids in snorers can decrease snoring frequency: a randomized placebo-controlled crossover trial Journal of Sleep Research, October 30, 2014    Clinical Article

20 Postoperative nasal debridement following functional endoscopic sinus surgery, a systematic review of the literature Clinical Otolaryngology, October 17, 2014    Review Article

Indexed Journals in Otolaryngology: American Journal of Otolaryngology, Clinical Otolaryngology, Auris Nasus Larynxmore