What is new in the management of salivary gland cancers
Current Opinion in Oncology, 04/28/2011
Adelstein DJ et al. – The recent identification of characteristic molecular signatures in specific histologic subtypes of salivary gland cancer has sparked interest in the potential for better diagnostic classification and more specific, molecularly targeted therapies. These are being intensively explored. Although the systemic management of these diseases has historically involved a number of relatively ineffective chemotherapeutic agents, newer and more promising schedules of chemotherapy and radiation are now being tested. Although the salivary gland cancers are uncommon, the growing understanding of their unique biologic characteristics is paving the way toward specific and personalized treatment. Enrollment of these patients onto carefully designed clinical trials is critical.