Genetic and clinical characteristics of head and neck paragangliomas in a chinese population

The Laryngoscope, 05/11/2012

Multifocal occurrence, potential malignancy, and genetic aspect should be considered in patients with head and neck Head and neck paragangliomas (PGLs). The high frequency of founder mutations in SDHB suggests a higher prevalence of malignancy, and the SDHD mutation is usually associated with familial cases.

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