Cystic fibrosis transmembrane conductance regulator modulation by the tobacco smoke toxin acrolein
The Laryngoscope, 05/10/2012Alexander NS et al.
The present study demonstrates that acrolein has complex but pronounced interaction with the major apical Cl–transport mechanism that uses cystic fibrosis transmembrane conductance regulator (CFTR). Further investigations are required to determine acrolein's impact as a tobacco smoke constituent on mucociliary transport.
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