Loss of heterozygosity (LOH) in tumour suppressor genes in benign and malignant mixed odontogenic tumours

Journal of Oral Pathology & Medicine, 04/30/2012

The results show a higher fractional allelic loss (FAL) in ameloblastic fibrosarcoma (AFS) compared to its benign counterparts and reveal a different pattern of Loss of heterozygosity (LOH) of tumour suppressor genes in AFS, which may regulate changes in tumour behaviour.

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