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Orthopedics - Clinical Pharmacology News & Articles

MDLinx Orthopedics, your most trusted resource for the latest medical articles! Topics covered range from Bone Metabolism, Foot & Ankle, Shoulder & Elbow, Hip, Knee, Hand & Wrist and much more. Our talented team of orthopedic medical editors vigorously rank, sort and summarize the top peer reviewed medical journals to ensure you receive the most pertinent information.

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Articles

Latest (1) Full Text Articles (32)
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

1 Effects of vancomycin, cefazolin and test conditions on the wear behavior of bone cement Journal of Arthroplasty, May 23, 2013    Clinical Article

Prior Articles

2 The effectiveness of teriparatide in the clinical practice-attenuation of the bone mineral density outcome by increasing age and bisphosphonate pretreatment Annals of Medicine, May 22, 2013    Evidence Based Medicine    Clinical Article

3 Efficacy of oral prednisolone in active ankylosing spondylitis: results of a double-blind, randomised, placebo-controlled short-term trial Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

4 Efficacy and safety of adalimumab in patients with non-radiographic axial spondyloarthritis: results of a randomised placebo-controlled trial (ABILITY-1) Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

5 A randomised, double-blind, multicentre, parallel-group, prospective study comparing the pharmacokinetics, safety, and efficacy of CT-P13 and innovator infliximab in patients with ankylosing spondylitis: the PLANETAS study Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

6 A randomized trial comparing monthly ibandronate and weekly alendronate for osteoporosis in patients with primary biliary cirrhosis Hepatology, May 21, 2013    Clinical Article

7 Similar response rates in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis after 1 year of treatment with etanercept: results from the ESTHER trial Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

8 Steroid injection for inferior heel pain: a randomised controlled trial Annals of Rheumatic Diseases, May 21, 2013    Clinical Article

9 Efficacy of duloxetine versus alternative oral therapies: an indirect comparison of randomised clinical trials in chronic low back pain European Spine Journal, May 20, 2013    Evidence Based Medicine    Clinical Article

10 Bisphosphonate use and subsequent hip fracture in South Korea Osteoporosis International, May 20, 2013    Clinical Article

11 Treatment of ankylosing spondylitis with TNF blockers: a meta-analysis Rheumatology International, May 20, 2013    Evidence Based Medicine    Review Article    Clinical Article

12 Decreased Risk of Wound Infection After Posterior Cervical Fusion With Routine Local Application of Vancomycin Powder Spine, May 20, 2013    Evidence Based Medicine    Clinical Article

13 Characterisation of in vivo release of gentamicin from polymethyl methacrylate cement using a novel method International Orthopaedics, May 20, 2013    Evidence Based Medicine

14 Cost-Effectiveness of Duloxetine in Chronic Low Back Pain: A Quebec Societal Perspective Spine, May 17, 2013    Evidence Based Medicine    Clinical Article

15 Prescription Opioids for Back Pain and Use of Medications for Erectile Dysfunction Spine, May 17, 2013    Evidence Based Medicine    Clinical Article

16 Influence of compliance on bone mineral density changes in postmenopausal women with early breast cancer on Anastrozole Journal of Cancer Research & Clinical Oncology, May 17, 2013    Clinical Article

17 Chinese Herbal Formula Huo-Luo-Xiao-Ling Dan Protects against Bone Damage in Adjuvant Arthritis by Modulating the Mediators of Bone Remodeling Full Text Evidence-based Complementary and Alternative Medicine , May 17, 2013    Clinical Article

18 Current Practice of Methylprednisolone Administration for Acute Spinal Cord Injury in Germany: A National Survey Spine, May 17, 2013    Evidence Based Medicine

19 Can Enoxaparin Reduce Thromboembolism Related Events After Primary TKA In Asian Patients? Journal of Arthroplasty, May 17, 2013    Review Article

20 Teriparatide and denosumab, alone or combined, in women with postmenopausal osteoporosis: the DATA study randomised trial The Lancet, May 16, 2013    Clinical Article

50 available pages FirstPrevious 1 2 3 4 5 6 7 8 9 10 Next Last

Clinical Pearls in Orthopedics

Highlights in Orthopedics

Zoledronic acid effective in fracture prevention after 1 year of treatment

As reported in the Journal of Bone and Mineral Research, the anti-fracture effect of zoledronic acid is apparent as early as 12 months after treatment and persists for at least 3 years. The study involved 9355 women with osteoporosis who were followed for 3 y. Compared with the placebo group, the ORs for fractures in the women 1, 2, and 3 years after treatment with zoledronic acid were 0.74, 0.53, and 0.61, respectively.

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Exercise + weight loss program effective in treating hip OA

As published in Physical Therapy, a combined 8-month exercise plus weight loss program in overweight or obese patients with hip OA (n=35) resulted in a 32.6% self-reported improvement in physical functioning, as well as pain and walking. This is the first report to demonstrate a benefit in patients with hip OA, which is consistent with the reported benefit of exercise plus weight loss in patients with knee OA.

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An alternative regimen for diabetic foot infections

As published in Infection, iv moxifloxacin (400 mg qd) is as effective as iv piperacillin/tazobactam (4.0/0.5 g tid) followed by oral amoxicillin/clavulanate (875/125 mg bid x 7-21 d) in the treatment of diabetic foot infections (69.9%-76.4% vs. 69.1%-78.8%, respectively).

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Most Popular Orthopedics Articles

Last month's top read Top Articles of 2012

1 The effect of magnesium added to levobupivacaine for femoral nerve block on postoperative analgesia in patients undergoing ACL reconstruction Knee Surgery, Sports Traumatology, Arthroscopy, April 22, 2013

2 The Efficacy and Safety of Bisphosphonates for Osteoporosis or Osteopenia in Crohns Disease: A Meta-Analysis Digestive Diseases and Sciences, April 19, 2013    Evidence Based Medicine

3 Comparison of Teriparatide and Bisphosphonate Treatment to Reduce Pedicle Screw Loosening After Lumbar Spinal Fusion Surgery in Postmenopausal Women With Osteoporosis From a Bone Quality Perspective Spine, April 16, 2013    Evidence Based Medicine

4 Tanezumab reduces osteoarthritic hip pain: Results of a randomized, double-blind, placebo-controlled phase 3 trial Arthritis & Rheumatism, April 2, 2013

5 Effects of Combined Application of Muscle Relaxants and Celecoxib Administration After Total Knee Arthroplasty (TKA) on Early Recovery: A Randomized, Double-Blind, Controlled Study Journal of Arthroplasty, April 8, 2013

6 Long-lasting beneficial effects of periradicular injection of meloxicam for treating chronic low back pain and sciatica Minerva Anestesiologica, April 5, 2013    Free full text

7 A multicentre, randomized, placebo- and active-controlled trial comparing the efficacy and safety of topical ketoprofen in Transfersome gel (IDEA-033) with ketoprofen-free vehicle (TDT 064) and oral celecoxib for knee pain associated with osteoarthritis Rheumatology, April 1, 2013

8 Treatment of the lumbar disc herniation with intradiscal and intraforaminal injection of oxygen-ozone Journal of Back and Musculoskeletal Rehabilitation, March 21, 2013

9 Gabapentin does not improve multimodal analgesia outcomes for total knee arthroplasty: a randomized controlled trial Canadian Journal of Anesthesia, March 13, 2013

10 Impact of autologous blood injections in treatment of mid-portion Achilles tendinopathy: double blind randomised controlled trial British Medical Journal, April 26, 2013    Evidence Based Medicine

11 Target-controlled infusion (Propofol) versus inhaled anaesthetic (Sevoflurane) in patients undergoing shoulder arthroscopic surgery Indian Journal of Anaesthesia, April 12, 2013    Free full text

12 Is discontinuation of clopidogrel necessary for intracapsular hip fracture surgery? Analysis of 102 hemiarthroplasties Journal of Orthopaedics and Traumatology, April 10, 2013    Free full text    Evidence Based Medicine

13 I.V. and perineural dexamethasone are equivalent in increasing the analgesic duration of a single-shot interscalene block with ropivacaine for shoulder surgery: a prospective, randomized, placebo-controlled study British Journal of Anesthesia, April 17, 2013

14 Steroid injections in the treatment of humeral unicameral bone cysts: long-term follow-up and review of the literature European Journal of Orthopaedic Surgery & Traumatology, April 10, 2013    Evidence Based Medicine

15 Effect of bisphosphonate use in patients with symptomatic and radiographic knee osteoarthritis: data from the Osteoarthritis Initiative Annals of Rheumatic Diseases, April 23, 2013

16 Antimicrobial Peptides and Proinflammatory Cytokines in Periprosthetic Joint Infection The Journal of Bone & Joint Surgery, April 4, 2013    Evidence Based Medicine

17 Results of infected total knee arthroplasty treated with arthroscopic debridement and continuous antibiotic irrigation system Indian Journal of Orthopaedics, February 14, 2013    Free full text

18 Economic Evaluation of Chlorhexidine Cloths on Healthcare Costs due to Surgical Site Infections Following Total Knee Arthroplasty Journal of Arthroplasty, April 3, 2013    Review Article

19 Efficacy and safety of tanezumab versus naproxen in the treatment of chronic low back pain Pain, March 14, 2013

20 Backfilling of iliac crest defects with hydroxyapatite-calcium triphosphate biphasic compound: a prospective, randomized computed tomography and patient-based analysis The Spine Journal, February 13, 2013

Indexed Journals in Orthopedics: Journal of Bone and Joint Surgery, Journal of Arthroplasty, Spine, The Kneemore

Other Topics in Orthopedics

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