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Orthopedics - Clinical Pharmacology News & Articles

MDLinx Orthopedics, your most trusted resource for the latest medical articles! Topics covered range from Bone Metabolism, Foot & Ankle, Shoulder & Elbow, Hip, Knee, Hand & Wrist and much more. Our talented team of orthopedic medical editors vigorously rank, sort and summarize the top peer reviewed medical journals to ensure you receive the most pertinent information.

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Articles

Latest (5) Full Text Articles (32)
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

881 Efficacy and safety of the selective cyclooxygenase-2 inhibitor celecoxib in the treatment of rheumatoid arthritis and osteoarthritis in Japan Digestion, November 1, 2010    Clinical Article

882 Multicenter Phase II trial assessing effectiveness of imatinib mesylate on relapsed or refractory KIT-positive or PDGFR-positive sarcoma Journal of Orthopaedic Science, October 29, 2010

883 Increased Antibiotic Release from a Bone Cement Containing Bacterial Cellulose Clinical Orthopedics and Related Research, October 29, 2010

884 Preoperative botulinum toxin test injections before muscle lengthening in cerebral palsy Journal of Orthopaedic Science, October 29, 2010

885 Felons and paronychias Current Orthopaedic Practice , October 29, 2010

886 Clustered metabolic risk and leisure-time physical activity in adolescents: effect of dose British Journal of Sports Medicine, October 27, 2010

887 Long-Term Safety of Using Local Anesthetic Injections in Professional Rugby League The American Journal of Sports Medicine, October 27, 2010

888 Feasibility and safety of ultrasound-guided caudal epidural glucocorticoid injections Joint, Bone, Spine, October 27, 2010

889 Development of natural calcium- and phosphate-donating microparticles and a new iontophoretic apparatus for the topical treatment of local osteoporosis. Preliminary in vitro and in vivo studies Joint, Bone, Spine, October 27, 2010

890 Less Promising Results With Sclerosing Ethoxysclerol Injections for Midportion Achilles Tendinopathy: A Retrospective Study The American Journal of Sports Medicine, October 26, 2010

891 Cortical and trabecular bone at the radius and tibia in postmenopausal breast cancer patients: A Peripheral Quantitative Computed Tomography (pQCT) study Bone, October 26, 2010

892 The role of rank-ligand inhibition in the treatment of postmenopausal osteoporosis Rheumatismo, October 25, 2010    Clinical Article

893 Osteogenic Protein-1 Delivered by Hydroxyapatite-coated Implants Improves Bone Ingrowth in Extracortical Bone Bridging Full Text Clinical Orthopedics and Related Research, October 25, 2010

894 Clinical, socio-demographic and radiological predictors of short-term outcome in rotator cuff disease Full Text BMC Musculoskeletal Disorders, October 21, 2010

895 Transbuccal fentanyl for rapid relief of orthopedic pain in the ED The American Journal of Emergency Medicine, October 21, 2010

896 FDA Warns Docs, Patients of Femoral Fracture Risk Linked to Some Bisphosphonates Full Text American Family Physician, October 20, 2010

897 Zoledronic acid infusion for prevention and treatment of osteoporosis Full Text International Journal of Women's Health, October 19, 2010

898 Systemic exposure to tobramycin after local antibiotic treatment with calcium sulphate as carrier material Archives of Orthopaedic and Trauma Surgery, October 18, 2010

899 Role of teriparatide in treatment of glucocorticoid-induced osteoporosis Full Text Therapeutics and Clinical Risk Management, October 15, 2010    Clinical Article

900 Serotonin syndrome in an orthopaedic patient secondary to linezolid therapy for MRSA infection Irish Journal of Medical Science, October 15, 2010

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Clinical Pearls in Orthopedics

Highlights in Orthopedics

Zoledronic acid effective in fracture prevention after 1 year of treatment

As reported in the Journal of Bone and Mineral Research, the anti-fracture effect of zoledronic acid is apparent as early as 12 months after treatment and persists for at least 3 years. The study involved 9355 women with osteoporosis who were followed for 3 y. Compared with the placebo group, the ORs for fractures in the women 1, 2, and 3 years after treatment with zoledronic acid were 0.74, 0.53, and 0.61, respectively.

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Exercise + weight loss program effective in treating hip OA

As published in Physical Therapy, a combined 8-month exercise plus weight loss program in overweight or obese patients with hip OA (n=35) resulted in a 32.6% self-reported improvement in physical functioning, as well as pain and walking. This is the first report to demonstrate a benefit in patients with hip OA, which is consistent with the reported benefit of exercise plus weight loss in patients with knee OA.

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An alternative regimen for diabetic foot infections

As published in Infection, iv moxifloxacin (400 mg qd) is as effective as iv piperacillin/tazobactam (4.0/0.5 g tid) followed by oral amoxicillin/clavulanate (875/125 mg bid x 7-21 d) in the treatment of diabetic foot infections (69.9%-76.4% vs. 69.1%-78.8%, respectively).

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Most Popular Orthopedics Articles

Last month's top read Top Articles of 2012

1 The influence of steroid administration on systemic response in laminoplasty for cervical myelopathy Archives of Orthopaedic and Trauma Surgery, May 6, 2013    Evidence Based Medicine

2 Efficacy of duloxetine versus alternative oral therapies: an indirect comparison of randomised clinical trials in chronic low back pain European Spine Journal, May 20, 2013    Evidence Based Medicine

3 Nonbenzodiazepine Sleep Medication Use and Hip Fractures in Nursing Home Residents JAMA Internal Medicine, May 15, 2013    Evidence Based Medicine

4 Thalidomide reduces recurrence of ankylosing spondylitis in patients following discontinuation of etanercept Rheumatology International, May 28, 2013

5 Bisphosphonate-related osteonecrosis of the jaw in non-malignant bone disease Rheumatology International, May 9, 2013

6 Topical glyceryl trinitrate treatment of chronic patellar tendinopathy: a randomised, double blind, placebo controlled clinical trial British Journal of Sports Medicine, May 29, 2013    Evidence Based Medicine

7 Cost-Effectiveness of Duloxetine in Chronic Low Back Pain: A Quebec Societal Perspective Spine, May 17, 2013    Evidence Based Medicine

8 Efficacy of continuous subacromial bupivacaine infusion for pain control after arthroscopic rotator cuff repair Journal of Shoulder and Elbow Surgery, May 14, 2013    Evidence Based Medicine

9 Feasibility and dose discovery analysis of zoledronic acid with concurrent chemotherapy in the treatment of newly diagnosed metastatic osteosarcoma European Journal of Cancer, May 10, 2013

10 Controlled-release oxycodone and naloxone in the treatment of chronic low back pain: A placebo-controlled, randomized study, Pain Research and Management, May 24, 2013

11 Tolerability of diclofenac sodium 1% gel with concomitant medications known to interact with diclofenac Therapeutics and Clinical Risk Management, May 3, 2013    Free full text

12 Effects of Combined Application of Muscle Relaxants and Celecoxib Administration After Total Knee Arthroplasty (TKA) on Early Recovery: A Randomized, Double-Blind, Controlled Study Journal of Arthroplasty, April 9, 2013

13 Cost-effectiveness of exercise therapy after corticosteroid injection for moderate to severe shoulder pain due to subacromial impingement syndrome: a trial-based analysis Rheumatology, May 1, 2013

14 Effects of vancomycin, cefazolin and test conditions on the wear behavior of bone cement Journal of Arthroplasty, May 23, 2013

15 Methylprednisolone Injections for the Treatment of Morton Neuroma A Patient-Blinded Randomized Trial The Journal of Bone & Joint Surgery, May 3, 2013    Evidence Based Medicine

16 Efficacy of oral prednisolone in active ankylosing spondylitis: results of a double-blind, randomised, placebo-controlled short-term trial Annals of Rheumatic Diseases, May 8, 2013

17 Patient experiences, attitudes and expectations towards receiving information about anti-TNF medication -- "It could give me two heads and I'd still try it!" BMC Musculoskeletal Disorders, May 13, 2013    Free full text    Evidence Based Medicine

18 Gabapentin does not improve multimodal analgesia outcomes for total knee arthroplasty: a randomized controlled trial Canadian Journal of Anesthesia, March 13, 2013

19 Treatment of the lumbar disc herniation with intradiscal and intraforaminal injection of oxygen-ozone Journal of Back and Musculoskeletal Rehabilitation, March 21, 2013

20 A phase III placebo- and oxycodone-controlled study of tanezumab in adults with osteoarthritis pain of the hip or knee Pain, April 30, 2013

Indexed Journals in Orthopedics: Journal of Bone and Joint Surgery, Journal of Arthroplasty, Spine, The Kneemore

Other Topics in Orthopedics

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