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Orthopedics - Clinical Pharmacology News & Articles

MDLinx Orthopedics, your most trusted resource for the latest medical articles! Topics covered range from Bone Metabolism, Foot & Ankle, Shoulder & Elbow, Hip, Knee, Hand & Wrist and much more. Our talented team of orthopedic medical editors vigorously rank, sort and summarize the top peer reviewed medical journals to ensure you receive the most pertinent information.

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Articles

Latest (2) Full Text Articles (32)
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

841 Effects of long-term corticosteroid usage on functional disability in patients with early rheumatoid arthritis, regardless of controlled disease activity Rheumatology International, December 28, 2010

842 Pain Relief for Reduction of Acute Anterior Shoulder Dislocations: A Prospective Randomized Study Comparing Intravenous Sedation With Intra-articular Lidocaine Journal of Orthopaedic Trauma, December 24, 2010    Clinical Article

843 Calcium-dependent signaling in Dupuytrens disease HAND, December 23, 2010    Clinical Article

844 Use of strontium as a treatment method for osteoporosis Current Osteoporosis Reports, December 22, 2010    Clinical Article

845 Diagnosis of Periprosthetic Joint Infections of the Hip and Knee Journal of the American Academy of Orthopedic Surgeons, December 21, 2010

846 Osteoporosis in Men: What has Changed Current Osteoporosis Reports, December 20, 2010    Clinical Article

847 Successful Monitoring of Transcranial Electrical Motor Evoked Potentials With Isoflurane and Nitrous Oxide in Scoliosis Surgeries Spine, December 16, 2010

848 The treatment of rheumatoid arthritis during pregnancy Rheumatology International, December 15, 2010    Clinical Article

849 Preformed gentamicin spacers in two-stage revision hip arthroplasty: functional results and complications International Orthopaedics, December 13, 2010    Clinical Article

850 Fluvastatin does not prevent the acute-phase response to intravenous zoledronic acid in post-menopausal women Bone, December 13, 2010    Clinical Article

851 First-line treatment with zoledronic acid as compared with clodronic acid in multiple myeloma (MRC Myeloma IX): A randomised controlled trial The Lancet, December 13, 2010

852 Infection in total hip replacement: meta-analysis International Orthopaedics, December 9, 2010    Evidence Based Medicine    Clinical Article

853 Evaluation of adequacy of short-course chemotherapy for extraspinal osteoarticular tuberculosis using 99mTc ciprofloxacin scan International Orthopaedics, December 9, 2010

854 Proposed new approach for treating Pagets disease of bone Irish Journal of Medical Science, December 9, 2010    Clinical Article

855 Injectable Collagenase Clostridium Histolyticum: A New Nonsurgical Treatment for Dupuytrens Disease The Journal of Hand Surgery, December 9, 2010

856 Effect of acetaminophen and fluvastatin on post-dose symptoms following infusion of zoledronic acid Osteoporosis International, December 8, 2010

857 Preventing osteoporosis with a tissue selective estrogen complex (TSEC) containing bazedoxifene/conjugated estrogens (BZA/CE) Osteoporosis International, December 8, 2010    Clinical Article

858 Comparison of intra-articular injections of Hyaluronic Acid and Corticosteroid in the treatment of Osteoarthritis of the hip in comparison with intra-articular injections of Bupivacaine. Design of a prospective, randomized, controlled study with blinding of the patients and outcome assessors Full Text BMC Musculoskeletal Disorders, November 30, 2010    Clinical Article

859 Addition of pamidronate to chemotherapy for the treatment of osteosarcoma Cancer, November 29, 2010    Clinical Article

860 Isoflavones versus hormone therapy for reduction of vertebral fracture risk: indirect comparison Menopause, November 23, 2010    Clinical Article

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Clinical Pearls in Orthopedics

Highlights in Orthopedics

Zoledronic acid effective in fracture prevention after 1 year of treatment

As reported in the Journal of Bone and Mineral Research, the anti-fracture effect of zoledronic acid is apparent as early as 12 months after treatment and persists for at least 3 years. The study involved 9355 women with osteoporosis who were followed for 3 y. Compared with the placebo group, the ORs for fractures in the women 1, 2, and 3 years after treatment with zoledronic acid were 0.74, 0.53, and 0.61, respectively.

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Exercise + weight loss program effective in treating hip OA

As published in Physical Therapy, a combined 8-month exercise plus weight loss program in overweight or obese patients with hip OA (n=35) resulted in a 32.6% self-reported improvement in physical functioning, as well as pain and walking. This is the first report to demonstrate a benefit in patients with hip OA, which is consistent with the reported benefit of exercise plus weight loss in patients with knee OA.

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An alternative regimen for diabetic foot infections

As published in Infection, iv moxifloxacin (400 mg qd) is as effective as iv piperacillin/tazobactam (4.0/0.5 g tid) followed by oral amoxicillin/clavulanate (875/125 mg bid x 7-21 d) in the treatment of diabetic foot infections (69.9%-76.4% vs. 69.1%-78.8%, respectively).

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Most Popular Orthopedics Articles

Last month's top read Top Articles of 2012

1 The influence of steroid administration on systemic response in laminoplasty for cervical myelopathy Archives of Orthopaedic and Trauma Surgery, May 6, 2013    Evidence Based Medicine

2 Efficacy of duloxetine versus alternative oral therapies: an indirect comparison of randomised clinical trials in chronic low back pain European Spine Journal, May 20, 2013    Evidence Based Medicine

3 Nonbenzodiazepine Sleep Medication Use and Hip Fractures in Nursing Home Residents JAMA Internal Medicine, May 15, 2013    Evidence Based Medicine

4 Thalidomide reduces recurrence of ankylosing spondylitis in patients following discontinuation of etanercept Rheumatology International, May 28, 2013

5 Bisphosphonate-related osteonecrosis of the jaw in non-malignant bone disease Rheumatology International, May 9, 2013

6 Topical glyceryl trinitrate treatment of chronic patellar tendinopathy: a randomised, double blind, placebo controlled clinical trial British Journal of Sports Medicine, May 29, 2013    Evidence Based Medicine

7 Cost-Effectiveness of Duloxetine in Chronic Low Back Pain: A Quebec Societal Perspective Spine, May 17, 2013    Evidence Based Medicine

8 Efficacy of continuous subacromial bupivacaine infusion for pain control after arthroscopic rotator cuff repair Journal of Shoulder and Elbow Surgery, May 14, 2013    Evidence Based Medicine

9 Feasibility and dose discovery analysis of zoledronic acid with concurrent chemotherapy in the treatment of newly diagnosed metastatic osteosarcoma European Journal of Cancer, May 10, 2013

10 Controlled-release oxycodone and naloxone in the treatment of chronic low back pain: A placebo-controlled, randomized study, Pain Research and Management, May 24, 2013

11 Tolerability of diclofenac sodium 1% gel with concomitant medications known to interact with diclofenac Therapeutics and Clinical Risk Management, May 3, 2013    Free full text

12 Effects of Combined Application of Muscle Relaxants and Celecoxib Administration After Total Knee Arthroplasty (TKA) on Early Recovery: A Randomized, Double-Blind, Controlled Study Journal of Arthroplasty, April 9, 2013

13 Cost-effectiveness of exercise therapy after corticosteroid injection for moderate to severe shoulder pain due to subacromial impingement syndrome: a trial-based analysis Rheumatology, May 1, 2013

14 Effects of vancomycin, cefazolin and test conditions on the wear behavior of bone cement Journal of Arthroplasty, May 23, 2013

15 Methylprednisolone Injections for the Treatment of Morton Neuroma A Patient-Blinded Randomized Trial The Journal of Bone & Joint Surgery, May 3, 2013    Evidence Based Medicine

16 Efficacy of oral prednisolone in active ankylosing spondylitis: results of a double-blind, randomised, placebo-controlled short-term trial Annals of Rheumatic Diseases, May 8, 2013

17 Patient experiences, attitudes and expectations towards receiving information about anti-TNF medication -- "It could give me two heads and I'd still try it!" BMC Musculoskeletal Disorders, May 13, 2013    Free full text    Evidence Based Medicine

18 Gabapentin does not improve multimodal analgesia outcomes for total knee arthroplasty: a randomized controlled trial Canadian Journal of Anesthesia, March 13, 2013

19 Treatment of the lumbar disc herniation with intradiscal and intraforaminal injection of oxygen-ozone Journal of Back and Musculoskeletal Rehabilitation, March 21, 2013

20 A phase III placebo- and oxycodone-controlled study of tanezumab in adults with osteoarthritis pain of the hip or knee Pain, April 30, 2013

Indexed Journals in Orthopedics: Journal of Bone and Joint Surgery, Journal of Arthroplasty, Spine, The Kneemore

Other Topics in Orthopedics

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