- Home
- Your Messages
-
Smartest Doc
Daily Quiz CompetitionTest your clinical knowledge against other physicians in the USA by taking our FREE daily quiz!
New! PHYSICIAN REVIEW
Thousands of questions to assess your knowledge and aid exam prep!
- Physician Jobs (564)
- More
- Other Specialty
Orthopedics - Basic Science/Genetics News & Articles
MDLinx Orthopedics, your most trusted resource for the latest medical articles! Topics covered range from Bone Metabolism, Foot & Ankle, Shoulder & Elbow, Hip, Knee, Hand & Wrist and much more. Our talented team of orthopedic medical editors vigorously rank, sort and summarize the top peer reviewed medical journals to ensure you receive the most pertinent information.
While perusing this page you may also find links to CME opportunities, orthopedic conferences and career opportunities.
Register today to gain access to exclusive content hand-picked by our physician editor D. Scott Cunningham, MD, PhD and clinical pearls from our Physician Review quizzes. As an MDLinx member you can also test your knowledge with our Smartest Doc daily quiz competition to see if you are indeed the Smartest Doc in America.
Your Unread Messages in Orthopedics
See All >> Messages include industry-sponsored communications and special communications from MDLinx-
Jill Baker
MDLinx Career Center
NPs and PAs play crucial role amid PCP shortage -
Smartest Doc Challenge
MDLinx
Clinical Pearls for Orthopedists -
MDLinx Reminder
MDLinx
Conference Center Upgraded with New Tools -
MDLinx Top Read
MDLinx
Running from that pile of unread journals? -
D Scott Cunningham MD, PhD
Site Editor, MDLinx
PTHrP (12-48) and NTx accurately predict breast cancer bone metastasis
Articles
Latest (1) Full Text Articles (20)961 Thrombospondin-2 regulates matrix mineralization in MC3T3-E1 pre-osteoblasts Bone, September 23, 2009
962 Differential expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in anterior cruciate ligament and medial collateral ligament fibroblasts after a mechanical injury Wound Repair and Regeneration, September 23, 2009
963 Bizarre Parosteal Osteochondromatous Proliferation of the Metatarsal: A Pediatric Case Report and Archival Review The Journal of Foot & Ankle Surgery, September 17, 2009
964 Antifibrotic medication using a combination of N-acetyl-L-cystein (NAC) and ACE inhibitors can prevent the recurrence of Dupuytren's disease Medical Hypotheses, September 16, 2009
965 Sonic hedgehog alleviates the inhibitory effects of high glucose on the osteoblastic differentiation of bone marrow stromal cells Bone, September 15, 2009
966 Control of RANKL gene expression Bone, September 15, 2009
967 Effects of selective serotonin reuptake inhibitors on bone health in adults: Time for recommendations about screening, prevention and management Bone, September 10, 2009
968 Chloride intracellular channel 1 regulates osteoblast differentiation Bone, September 9, 2009
969 Patterns of FGF-23, DMP1, and MEPE expression in patients with chronic kidney disease Bone, September 9, 2009
970 The calcium-sensing receptor in bone cells: A potential therapeutic target in osteoporosis Bone, September 8, 2009
971 Mechanical stress induces Interleukin-11 expression to stimulate osteoblast differentiation Bone, September 8, 2009
972 Association of the calcitonin gene polymorphism with osteoarthritis of the knee in a Mexican mestizo population The Knee, September 8, 2009
973 Heat-shock protein 70 gene polymorphism is associated with the severity of diabetic foot ulcer and the outcome of surgical treatment British Journal of Surgery, September 4, 2009
974 HSD11B1 polymorphisms predicted bone mineral density and fracture risk in postmenopausal women without a clinically apparent hypercortisolemia Bone, September 3, 2009
975 Vitamin D receptor gene polymorphisms modulate the skeletal response to vitamin D supplementation in healthy girls Bone, September 3, 2009
976 Differential Effects of Culture-expanded Bone Marrow Cells on the Regeneration of Bone Between the Femoral and the Tibial Lengthenings Journal of Pediatric Orthopaedics , September 3, 2009
977 Mesomelic dysplasia with acral synostoses Verloes-David-Pfeiffer type: Follow-up study documents progressive clinical course American Journal of Medical Genetics Part A, September 3, 2009
978 The dependency of solute diffusion on molecular weight and shape in intact bone Bone, September 2, 2009
979 Neutrophil CD64 expression in the diagnosis of local musculoskeletal infection and the impact of antibiotics The Bone & Joint Journal, September 1, 2009
980 DR5 and DcR2 are Expressed in Human Lumbar Intervertebral Discs Spine, August 31, 2009
Clinical Pearls in Orthopedics
- Almost half of the ankle sprains referred to orthopedic departments show no ligament injury on MRI, since. Isolated bone bruises and tendon injuries share the same clinical signs as ankle sprains
- Researchers found that visceral adiposity may also adversely influence bone mass during adolescence.
- Regional differences may exist in the proportion of prevalent and incident major fractures that are hip fractures; North American (16%, 17%), northern Europe (13%, 12%) and southern Europe (10%, 10%).
Highlights in Orthopedics
Zoledronic acid effective in fracture prevention after 1 year of treatment
As reported in the Journal of Bone and Mineral Research, the anti-fracture effect of zoledronic acid is apparent as early as 12 months after treatment and persists for at least 3 years. The study involved 9355 women with osteoporosis who were followed for 3 y. Compared with the placebo group, the ORs for fractures in the women 1, 2, and 3 years after treatment with zoledronic acid were 0.74, 0.53, and 0.61, respectively.
Read the article summaryExercise + weight loss program effective in treating hip OA
As published in Physical Therapy, a combined 8-month exercise plus weight loss program in overweight or obese patients with hip OA (n=35) resulted in a 32.6% self-reported improvement in physical functioning, as well as pain and walking. This is the first report to demonstrate a benefit in patients with hip OA, which is consistent with the reported benefit of exercise plus weight loss in patients with knee OA.
Read the article summaryAn alternative regimen for diabetic foot infections
As published in Infection, iv moxifloxacin (400 mg qd) is as effective as iv piperacillin/tazobactam (4.0/0.5 g tid) followed by oral amoxicillin/clavulanate (875/125 mg bid x 7-21 d) in the treatment of diabetic foot infections (69.9%-76.4% vs. 69.1%-78.8%, respectively).
Read the article summaryMost Popular Orthopedics Articles
Last month's top read Top Articles of 20121 Injection of human umbilical tissue-derived cells into the nucleus pulposus alters the course of intervertebral disc degeneration in vivo The Spine Journal, April 1, 2013 Review Article
2 The effects of microenvironment in mesenchymal stem cell-based regeneration of intervertebral disc The Spine Journal, April 2, 2013 Review Article
3 Bone mineral density testing: Is a T score enough to determine the screening interval? Cleveland Clinic Journal of Medicine, April 3, 2013 Free full text
4 Opportunistic Screening for Osteoporosis Using Abdominal Computed Tomography Scans Obtained for Other Indications Annals of Internal Medicine, April 17, 2013
5 Role of hormones in cartilage and joint metabolism: understanding an unhealthy metabolic phenotype in osteoarthritis Menopause, April 26, 2013 Review Article
6 Overview of Cartilage Biology and New Trends in Cartilage Stimulation Foot and Ankle Clinics, March 20, 2013 Review Article
7 Surgery versus Physical Therapy for a Meniscal Tear and Osteoarthritis New England Journal of Medicine, March 27, 2013
8 MicroRNA Functions in Osteogenesis and Dysfunctions in Osteoporosis Current Osteoporosis Reports, April 24, 2013
9 Fibrous Dysplasia and Fibroblast Growth Factor-23 Regulation Current Osteoporosis Reports, April 1, 2013 Review Article
10 KIAA1199, a deafness gene of unknown function, is a new hyaluronan binding protein involved in hyaluronan depolymerization Proceedings of the National Academy of Sciences of the United States of America, April 18, 2013 Review Article
11 Regulation of Wnt/{beta}-catenin signaling within and from osteocytes Bone, March 28, 2013 Review Article
12 Notch Signaling and Bone Remodeling Current Osteoporosis Reports, March 25, 2013 Review Article
13 Relationship between postmenopausal osteoporosis and the components of clinical sarcopenia Maturitas, April 15, 2013
14 Mechanical Regulation of Skeletal Development Current Osteoporosis Reports, March 15, 2013 Review Article
15 The Role of Muscle in Bone Repair: The Cells, Signals, and Tissue Responses to Injury Current Osteoporosis Reports, April 19, 2013 Review Article
Indexed Journals in Orthopedics: Journal of Bone and Joint Surgery, Journal of Arthroplasty, Spine, The Knee more
Other Topics in Orthopedics
Register now to view all the MDLinx contents (FREE)!
- Stay current on the latest literature, research and clinical news
- Get special communications and offers from MDLinx and our sponsors
- Receive invitations to paid market research
Login
Stay current - Media Tool
♦ Subscribe to our free RSS feeds:
Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More ♦
♦ Follow Us on Twitter
Twitter is a rich source of instantly updated information. Join today and follow @MDLinx to start receiving tweets. Learn More ♦
Close