MDLinx Orthopedics, your most trusted resource for the latest medical articles! Topics covered range from Bone Metabolism, Foot & Ankle, Shoulder & Elbow, Hip, Knee, Hand & Wrist and much more. Our talented team of orthopedic medical editors vigorously rank, sort and summarize the top peer reviewed medical journals to ensure you receive the most pertinent information.
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941 Heightened Flexor Withdrawal Response in Individuals with Knee Osteoarthritis is Modulated by Joint Compression and Joint Mobilization The Journal of Pain, December 2, 2009
942 Relationship Between Genotype and Skeletal Phenotype in Children and Adolescents With Osteogenesis Imperfecta Journal of Bone and Mineral Research, December 1, 2009
943 Immunolocalization of BMPs, BMP antagonists, receptors, and effectors during fracture repair Bone, December 1, 2009
944 The expression of Gli3, regulated by HOXD13, may play a role in idiopathic congenital talipes equinovarus Full Text BMC Musculoskeletal Disorders, November 23, 2009
945 Increased Dickkopf-1 expression accelerates bone cell apoptosis in femoral head osteonecrosis Bone, November 23, 2009
946 Use of polyetheretherketone spacer and recombinant human bone morphogenetic protein-2 in the cervical spine: a radiographic analysis The Spine Journal, November 23, 2009
947 A health economic analysis of the use of rhBMP-2 in Gustilo–Anderson grade III open tibial fractures for the UK, Germany, and France Injury, November 20, 2009
948 Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuse Bone, November 17, 2009
949 CDP/Cut is an Osteoblastic Co-Activator of the Vitamin D Receptor (VDR) Journal of Bone and Mineral Research, November 17, 2009
950 Expression of TRAIL and death receptor DR4 in Palmer type 2 TFCC lesions Archives of Orthopaedic and Trauma Surgery, November 16, 2009
951 HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage Bone, November 16, 2009
952 Transplantation of Human Marrow Stromal Cells and Mono-Nuclear Bone Marrow Cells Into the Injured Spinal Cord: A Comparative Study Spine, November 13, 2009
953 Hip Geometry Variation is Associated With Bone Mineralization Pathway Gene Variants: The Framingham Study Journal of Bone and Mineral Research, November 13, 2009
954 The COL5A1 Gene Is Associated With Increased Risk of Anterior Cruciate Ligament Ruptures in Female Participants The American Journal of Sports Medicine, November 12, 2009
955 Osteoarthritic cartilage chondrocytes alter subchondral bone osteoblast differentiation via MAPK signalling pathway involving ERK1/2 Bone, November 12, 2009
956 Bone signaling pathways and treatment of osteoporosis Expert Review of Endocrinology & Metabolism, November 10, 2009 Review Article
957 The Effects of Farnesol on Staphylococcus aureus Biofilms and Osteoblasts The Journal of Bone & Joint Surgery, November 6, 2009
958 Differentiation of Intervertebral Notochordal Cells Through Live Automated Cell Imaging System In Vitro Spine, November 5, 2009
959 Ketorolac But Not Morphine Exerts Inflammatory and Metabolic Effects in Synovial Membrane After Knee Arthroscopy: A Double-Blind Randomized Prospective Study Using the Microdialysis Technique Regional Anesthesia and Pain Medicine, November 4, 2009
960 Temporal pattern of gene expression and histology of stress fracture healing Bone, November 3, 2009
As reported in the Journal of Bone and Mineral Research, the anti-fracture effect of zoledronic acid is apparent as early as 12 months after treatment and persists for at least 3 years. The study involved 9355 women with osteoporosis who were followed for 3 y. Compared with the placebo group, the ORs for fractures in the women 1, 2, and 3 years after treatment with zoledronic acid were 0.74, 0.53, and 0.61, respectively.
Read the article summaryAs published in Physical Therapy, a combined 8-month exercise plus weight loss program in overweight or obese patients with hip OA (n=35) resulted in a 32.6% self-reported improvement in physical functioning, as well as pain and walking. This is the first report to demonstrate a benefit in patients with hip OA, which is consistent with the reported benefit of exercise plus weight loss in patients with knee OA.
Read the article summaryAs published in Infection, iv moxifloxacin (400 mg qd) is as effective as iv piperacillin/tazobactam (4.0/0.5 g tid) followed by oral amoxicillin/clavulanate (875/125 mg bid x 7-21 d) in the treatment of diabetic foot infections (69.9%-76.4% vs. 69.1%-78.8%, respectively).
Read the article summary1 Nrp2 deficiency leads to trabecular bone loss and is accompanied by enhanced osteoclast and reduced osteoblast numbers Bone, May 7, 2013 Review Article
2 Molecular Distinction of Chondrosarcoma From Chondroblastic Osteosarcoma Through IDH1/2 Mutations American Journal of Surgical Pathology , May 15, 2013
3 Single-stage cartilage repair in the knee with microfracture covered with a resorbable polymer-based matrix and autologous bone marrow concentrate The Knee, May 3, 2013 Review Article
4 Enhanced migration of human bone marrow stromal cells in modified collagen hydrogels International Orthopaedics, May 6, 2013 Review Article
5 Kuskokwim syndrome, a recessive congenital contracture disorder, extends the phenotype of FKBP10 mutations Human Mutation, May 29, 2013 Review Article
6 The Effect of Recombinant Human Bone Morphogenetic Protein-2 in Single-Level Posterior Lumbar Interbody Arthrodesis The Journal of Bone & Joint Surgery, May 16, 2013 Evidence Based Medicine
7 IgG subclass antibodies to human and bacterial HSP60 are not associated with disease activity and progression over time in axial spondyloarthritis Arthritis Research & Therapy, May 28, 2013 Review Article
8 Mortality of Congenital Osteochondrodysplasias: A Nationwide Registry-Based Study American Journal of Medical Genetics Part A, May 22, 2013 Review Article
9 Transforming Growth Factor Beta 1 Is a Novel Susceptibility Gene for Adolescent Idiopathic Scoliosis Spine, May 20, 2013 Evidence Based Medicine
10 Osteogenesis imperfecta Orthopaedics and Trauma, May 29, 2013 Review Article
11 Expression and Relationship of Proinflammatory Chemokine RANTES/CCL5 and Cytokine IL-1{beta} in Painful Human Intervertebral Discs Spine, May 13, 2013 Review Article
12 An exon polymorphism of programmed cell death 1 gene is associated with both the susceptibility and thoracolumbar kyphosis severity of ankylosing spondylitis in a Chinese Han population Journal of Orthopaedic Science, April 26, 2013 Review Article
13 Use of Recombinant Human Bone Morphogenetic Protein-2 With Local Bone Graft Instead of Iliac Crest Bone Graft in Posterolateral Lumbar Spine Arthrodesis Spine, May 20, 2013 Evidence Based Medicine
14 Appearance of Osteolysis with Melorheostosis: Redefining the Disease or a New Disorder? A Novel Case Report with Multimodality Imaging The Journal of Foot & Ankle Surgery, May 17, 2013 Review Article
15 Role of hormones in cartilage and joint metabolism: understanding an unhealthy metabolic phenotype in osteoarthritis Menopause, April 26, 2013 Review Article
16 Ten-year RSA-measured migration of the Exeter femoral stem The Bone & Joint Journal, May 1, 2013 Review Article
17 Initial Tension Loss in Cerclage Cables Journal of Arthroplasty, April 25, 2013 Review Article
18 Clinical and Molecular Analysis in Families With Autosomal Recessive Osteogenesis Imperfecta Identifies Mutations in Five Genes and Suggests Genotype-Phenotype Correlations American Journal of Medical Genetics Part A, May 1, 2013 Review Article
19 Bone mineral density testing: Is a T score enough to determine the screening interval? Cleveland Clinic Journal of Medicine, April 3, 2013 Free full text
20 Effects of selenium coating of orthopaedic implant surfaces on bacterial adherence and osteoblastic cell growth The Bone & Joint Journal, May 1, 2013 Review Article
Indexed Journals in Orthopedics: Journal of Bone and Joint Surgery, Journal of Arthroplasty, Spine, The Knee more
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