Risk factors for the development of vertebral fractures after percutaneous vertebroplasty

Journal of Bone and Mineral Research, 02/21/2013

The authors have recently observed an increased risk for vertebral fractures (VF) in a randomized controlled trial comparing the analgesic effect of vertebroplasty (VP) versus conservative treatment in symptomatic VF. The aim of the present study was to evaluate the risk factors related to the development of VF after VP in these patients. Nearly 30% of patients with osteoporotic VF treated with VP had a new VF after the procedure. Age, especially over 80 years, the presence of inferior disk cement leakage after the procedure, the number of cemented vertebrae and low 25OHD serum levels were related to the development of new VF in these patients; the latter indicating the need to correct vitamin D deficiency prior to performing VP.

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