Determination of cephazolin, ceftazidime, and ceftriaxone distribution in nucleus pulposus

Archives of Orthopaedic and Trauma Surgery, 04/25/2012

The antibiotics of cephazolin, ceftazidime, and ceftriaxone had concentration in the nucleus pulposus (NP) tissue, which was higher than the stated MIC. Ceftazidime had highest penetration in to NP tissue, and ceftriaxone had the lowest penetration in to NP tissue.

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