Predicting longitudinal trajectory of bone mineral density in paediatric systemic lupus erythematosus patients
Annals of Rheumatic Diseases, 04/06/2012
Lim LSH et al. – The lumbar spine (LS) bone mineral density (BMD) of paediatric systemic lupus erythematosus (pSLE) patients followed a general deteriorating trend over time and could be predicted by a combination of pubertal status at diagnosis, interval cumulative doses of steroids and weight z–scores. Interval cumulative steroid dose represents an important target that clinicians may modify to ameliorate deteriorating BMD trajectory over time.