Transmenopausal changes in trabecular bone quality

Journal of Bone and Mineral Research, 08/22/2013

Bone strength depends on its amount and quality. Bone quality includes its structural and material properties. Bone material properties are dependent on bone turnover rates. Remodeling rates are significantly increased immediately following menopause. The results indicate that significant changes (specifically in mineral / matrix ratio) were evident at actively bone forming surfaces, while the relative proteoglycan content was altered at resorbing surfaces. These changes were not accompanied by altered mineral content or quality as monitored by Raman microspectroscopic analysis.

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