Predictors of fracture while on treatment with oral bisphosphonates: A population-based cohort study

Journal of Bone and Mineral Research, 06/13/2013

Although oral bisphosphonates (BP) are highly effective in preventing fractures, some patients will fracture while on treatment. Even among high compliers, 3.4% of oral BP users will fracture every year. Older age, underweight, vitamin D deficiency, proton pump inhibitors (PPI) use, previous fracture and inflammatory arthritides increase risk. Monitoring strategies and/or alternative therapies should be considered for these patients.

Print Article Summary Cat 2 CME Report