Association of serum fibroblast growth factor 23 (FGF23) and incident fractures in older men: the osteoporotic fractures in men (MrOS) study

Journal of Bone and Mineral Research, 05/16/2013

Normal mineral metabolism is critical for skeletal integrity and recently serum fibroblast Growth factor 23 (FGF23) levels were found to be directly related to overall fracture risk in elderly Swedish Men. To confirm this association, the authors performed a prospective case–cohort study to understand the relation of FGF23 and fracture risk in older Caucasian men enrolled in the Osteoporotic Fractures in Men (MrOS) Study. Serum FGF23 levels are not associated with incident fractures in elderly men overall. However, higher levels of serum FGF23 are associated with fracture risk in those with poor renal function.

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