Hepatitis C co-infection and severity of liver disease as risk factors for osteoporotic fractures among HIV-infected patients

Journal of Bone and Mineral Research, 05/16/2013

Osteoporosis is increasingly reported in the aging HIV–positive population, and co–infection with hepatitis C virus (HCV) may further increase the risk of osteoporosis. However, it remains unclear whether HCV–related increased fracture risk is a function of the severity of liver disease. Among HIV–infected patients, severity of liver disease partly explains the HCV–associated increased risk of osteoporotic fractures. Other determinants of this increased risk remain to be defined.

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