Lipoproteins are an important bacterial component responsible for bone destruction through the induction of osteoclast differentiation and activation
Journal of Bone and Mineral Research, 05/01/2013Kim J et al.
Bacterial infection can cause inflammatory bone diseases accompanied by the bone destruction due to excess generation of osteoclasts. Although lipoproteins are one of the major immuno–stimulating components of bacteria, little is known about their effects on bone metabolism. The results suggest that lipoprotein might be an important bacterial component responsible for bone destruction during bacterial infections through augmentation of osteoclast differentiation and activation.
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